Slc11a1 rs7608307
Webof SLC11A1 gene is very important due to its association with resistance/ susceptibility to various intracellular pathogens in human as well as in livestock species. The SLC11A1 gene, formerly known as natural resistance-associated macrophage protein 1 (NRAMP1) encodes an integral membrane protein regulating the activity of macrophages. WebNov 9, 2024 · Using univariate COX regression analysis and hub gene analysis (cytoHubba), SLC11A1 was identified as the only candidate gene for subsequent analysis. CIBERSORT, …
Slc11a1 rs7608307
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WebResults: (adjust pvalue < 0.01 and log FC ≥ 1). A cluster of 10 genes including CYBA, SLC11A1, FCER1G, ITGAM, ITGB2, CD53, ITGAX, VAMP8, CLEC5A,and CD300Awere found to be significant. WebMar 9, 2024 · The Slc11a1 encodes a late endosomal/lysosomal protein/divalent cation transporter, which regulates iron homeostasis in macrophages. results demonstrate a role for Slc11a1 (Nramp1) in modifying susceptibility to type 1 diabetes and illustrate that RNAi can be used to study causal genes in a mammalian model organism
WebMay 3, 2024 · Studies have demonstrated that the solute carrier family 11 member 1 (SLC11A1) is heavily glycosylated and phosphorylated in macrophages. However, the mechanisms of SLC11A1 phosphorylation, and the effects of phosphorylation on SLC11A1 activity remain largely unknown. Here, the tyrosine phosphorylation of SLC11A1 is … WebThis gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions …
WebFeb 9, 2024 · SLC11A1 is located in monocyte phagolysosomes that help to limit M. tuberculosis growth by transferring divalent cations across the membrane. Genetic variation in SLC11A1 may alter its... WebDec 7, 2007 · Slc11a1 (formerly Nramp1) is a proton/divalent cation transporter that regulates cation homeostasis in macrophages. Slc11a2 mediates divalent cation uptake via the gut and delivery into cells. The mode of action of the two transporters remains controversial. Heterologous expression in frog oocytes s …
WebJan 15, 2024 · This study suggested that rs7573065 in SLC11A1 was associated with an increased risk and poor OS of prostate cancer. Our findings may provide evidence for genetic variants in autophagy-lysosome pathway as the risk and prognostic biomarkers for prostate cancer.
WebSlc11a1 (formerly Nramp1) is a proton/divalent cation transporter that regulates cation homeostasis in macrophages. Slc11a2 mediates divalent cation uptake via the gut and delivery into cells. The mode of action of the two transporters remains controversial. Heterologous expression in frog oocytes shows Slc11a2 is a symporter, whereas Slc11a1 … bus timetable victor harbor to adelaideWeb10 kt semi solid braclet. Ships to you. $8. Vintage Copper Revere Ware Tea Kettle. Indianapolis, IN. $20. 10 kt semi solid braclet. Ships to you. $20. bus timetable wadebridge to padstowWebMar 21, 2024 · Decreased expression of the long non-coding RNA SLC7A11-AS1 predicts poor prognosis and promotes tumor growth in gastric cancer. (PMID: 29348845) Luo Y … bus timetable wellington to tauntonWebSLC11A1 INFORMATION. Proteini. Full gene name according to HGNC. Solute carrier family 11 member 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. SLC11A1 (LSH, NRAMP, NRAMP1) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). bus timetable waterbeach to cambridgeWebIn addition, we observed that the CC genotype of rs4674301 was correlated with increased TB risk in females (p = 0.043). Our results demonstrated the relationships between polymorphisms (rs7608307, rs4674301, and rs13062) in or near the SLC11A1 gene and age- and sex-specific TB risk in the northwest Chinese Han population. cc in the circleWebThis meta-analysis suggests that polymorphisms in the SLC11A1 gene contribute to TB (both PTB and EPTB), particularly in Asians. BACKGROUND Polymorphisms in SLC11A1 gene have been extensively studied for an association with tuberculosis (TB); however, results from replication studies have been inconsistent. OBJECTIVE To comprehensively … cc interventionWebContact Us: Office: (317) 788-3280 Fax: (317) 788-3490 Studio: (317) 788-3314 (866) 600-9914 UIndy Radio Studio: (317) 788-6120 c c international