Thiazide diuretics and hip fractures
Web19 Feb 2024 · However, our study shows a positive role of thiazide diuretics and beta blockers on the bone mineral density of the lumbar spine in osteoporotic hypertensive postmenopausal women. Further prospective studies with larger sample sizes and narrow age range are needed to evaluate the relationship between BMD and hypertension. … WebAn alleged association of chronic use of thiazide diuretics with an increased risk of bone fragility fractures has been highlighted by a relatively recent prospective cohort study. However, the concept that thiazides exert a beneficial effect on osteoporosis is still a predominant view.
Thiazide diuretics and hip fractures
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Web9 rows · 1 Nov 2024 · The biological mechanisms underlying the association between thiazide diuretics and the risk of ... Web21 Nov 2024 · Use of thiazide diuretics was associated with significantly reduced risk of fracture in patients with acute status including new-onset stroke or spinal cord injury (RR: 0.70, 95% CI: 0.57 to 0.86, p < 0.001), but not in those with good conditions such as community-dwelling population or hypertensive patients (p for subgroup difference = 0.02).
Web1 Nov 2024 · Introduction Thiazides diuretics reduce urinary calcium excretion and may inhibit bone resorption, but their role in preventing hip fracture remains conflicting. Using … WebA Cochrane review found tentative evidence that thiazide exposure was associated with a reduced risk of hip fracture. A secondary analysis of data from the ALLHAT study found that chlortalidone reduced risk of hip and pelvis fracture. ... As with other thiazide diuretics, chlortalidone crosses the placenta and is excreted in breast milk ...
Web29 Nov 2005 · A direct comparison of risk estimates showed a significantly higher risk of fractures at the hip ( P = 0.02) and forearm ( P = 0.04), as well as a borderline significantly higher risk of any fracture ( P = 0.05) in users of furosemide compared with users of bumetanide ( Table 4 ). Web22 Nov 2016 · Thiazide diuretics are associated with a reduced risk of hip and pelvic fractures compared with treatment with other antihypertensive drugs, according to a …
Web1 May 2024 · by Patricia Inacio, PhD May 1, 2024. Long-term use of thiazide diuretics — a hypertension medication — may lower the risk of bone fractures, particularly hip fractures, … rock it natural cosmetics ltdWeb24 Dec 2024 · The controversial relationship between thiazide diuretics and fractures involves conflicting mechanisms. On the one hand, thiazide could exert beneficial effects on the bone via decreasing... rockit monitor speakersWeb1 Jul 1991 · Thiazide diuretics appear to reduce the risk of hip fracture based on observational studies, and randomized controlled trials are needed to confirm these … rockit music powell river bcWeb16 Sep 2003 · The study showed that people who had used thiazide diuretics for a year or more were about half as likely to suffer a hip fracture than those who had never used … rock it natural stone clarksville arWebIntroduction: Thiazides diuretics reduce urinary calcium excretion and may inhibit bone resorption, but their role in preventing hip fracture remains... DOAJ is a community … other word of heritageWebA total of 18 observational studies that looked at the relationship between diuretics and fracture were located, of which 13, involving 29,600 subjects, had extractable data on … rockit natural stone in okWebVertebral fracture is the most common type of osteoporotic fracture. While thiazide diuretics, which are commonly prescribed for the treatment of hypertension, decrease calciuria, they may also induce hyponatremia, which has been associated with increased vertebral fracture risk. rock it natural stone oklahoma